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Case Report
Breast schwannoma: A case report and brief review of literature
1 Washington State University Elson S. Floyd College of Medicine, Spokane, WA, USA
2 Department of Pathology, Overlake Medical Center, Bellevue, WA, USA
3 Department of Breast Surgery, Overlake Cancer Center, Overlake Medical Center, Bellevue, WA, USA
Address correspondence to:
April Phantana-angkool
MD, Department of Breast Surgery, Overlake Medical Center, 1135 116th Ave NE, Bellevue, WA 98004,
USA
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Article ID: 100152Z12HR2025
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Ryou H, Ji H, Phantana-angkool A. Breast schwannoma: A case report and brief review of literature. J Case Rep Images Surg 2025;11(1):19–24.ABSTRACT
Introduction: Schwannoma is a type of tumor deriving from Schwann cells of the peripheral nerves. Schwannomas have the potential to develop anywhere in the body where peripheral nerves exist; breast schwannomas are particularly rare.
Case Report: This case reports an occurrence of breast schwannoma observed over a five-year period in Washington. Initial identification of the mass presented with low-level internal echoes, moderate peripheral vascularity, and questionable internal vascularity. Five-year follow-up demonstrated mild increase in size and development from an initially well circumscribed hypoechoic lesion to growing not-well circumscribed margins. Core biopsy and pathology showed evidence of palisading and diffusely positive S100, confirming diagnosis of schwannoma. The patient underwent surgical excision.
Conclusion: This case opens discussion for the potential of long-term follow-up for benign masses as alternatives to immediate surgical excision.
Keywords: Breast surgery, Imaging, Palpable breast mass, Schwannoma
SUPPORTING INFORMATION
Author Contributions
Haneul Ryou - Substantial contributions to conception and design, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Hongxiu Ji - Substantial contributions to conception and design, Drafting the article, Final approval of the version to be published
April Phantana-angkool - Substantial contributions to conception and design, Acquisition of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2025 Haneul Ryou et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
